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BergenBio Fundamentale Forhold (BGBIO)

BerGenBio - Invitation to conference call: interim update on Ph II clinical programme with selective AXL inhibitor bemcentinib being presented at ASCO

Bergen, Norway, 29 May 2018 - BerGenBio ASA (OSE:BGBIO) will host a conference
call on Monday, 4 June at 8:30 AM CEST to present updated interim clinical and
biomarker results from its ongoing Phase II development programme with selective
AXL inhibitor bemcentinib. The data will be presented at the Annual American
Society of Clinical Oncology (ASCO) meeting and at a reception hosted by
BerGenBio (details below).
Conference call details:

The call will be hosted by BerGenBio senior management and take place on:

Monday, 4 June 2018 at 8:30 AM CEST.

To take part, please dial in 5-10 minutes prior to the scheduled start using
below phone number and confirmation code 1068189:

Norway +47 2100 2608

United Kingdom +44 (0) 330 336 9106

United States +1 323 794 2594

A slide deck presentation to accompany the call will be made available
at www.bergenbio.com in the Investors / Presentations section from 8:00 AM CEST
on 4 June 2018.

Presentations to be made during the annual ASCO meeting:

Saturday 2 June, 6:00 - 8:00 PM CDT, Chicago School of the Art Institute,
Chicago, IL

· BerGenBio reception
· New interim Phase II clinical trial data with bemcentinib and selected pre
-clinical data to be discussed by BerGenBio principal investigators and invited
key opinion leaders
· For further details and to receive an invitation, please email to
asco2018@bergenbio.com

Monday 4 June, 8:00 AM - 11:30 AM CDT, ASCO Annual Meeting, McCormick Center,
Chicago, IL

· Interim clinical data from clinical trial ref. BGBC008 - Poster Board: #292,
Abstract 3078
· Interim clinical data from clinical trial ref. BGBC003 - Poster Board: #80,
Abstract 7020
· To be discussed at the Poster Discussion Session. 11:30 AM - 12:45 PM CDT
· Biomarker study - Poster Board: #385, Abstract 2559

Monday 4 June, 1:15 PM - 4:45 PM CDT, ASCO Annual Meeting, McCormick Center,
Chicago, IL

· Interim clinical data from clinical trial ref. BGBIL006 - Poster Board:
#375, Abstract 9548

The posters presented at ASCO will be made available www.bergenbio.comin the
Investors / Presentations section at the time of presentation.

-End-

About BerGenBio ASA

BerGenBio ASA is a clinical-stage biopharmaceutical company focused on
developing a pipeline of first-in-class AXL kinase inhibitors as a potential
cornerstone of combination cancer therapy. The Company is a world leader in
understanding the essential role of AXL kinase in mediating aggressive disease,
including immune evasive, drug resistant, metastatic solid and haematological
cancers.

BerGenBio’s lead product, bemcentinib (BGB324), is a selective, potent and
orally bio-available small molecule AXL inhibitor in four Company sponsored
Phase II clinical trials in major cancer indications, with read-outs anticipated
during 2018. It is the only selective AXL inhibitor in clinical development.

The Company sponsored clinical trials are:

· Bemcentinib with TARCEVA® (erlotinib) in advanced EGFR mutation driven non
-small cell lung cancer (NSCLC)
· Bemcentinib with KEYTRUDA in advanced adenocarcinoma of the lung, and
· Bemcentinib with KEYTRUDA in triple-negative breast cancer (TNBC).
· Bemcentinib as a single agent and combination therapy in acute myeloid
leukaemia (AML) / myeloid dysplastic syndrome (MDS)

The clinical trials combining bemcentinib with KEYTRUDA in adenocarcinoma of the
lung and TNBC are conducted in collaboration with Merck & Co., Inc. (Kenilworth,
NJ, USA), through a subsidiary.

In addition, a number of investigator-sponsored trials are underway, including a
trial to investigate bemcentinib with either MEKINIST® (trametinib) plus
TAFINLAR® (dabrafenib) or KEYTRUDA in advanced melanoma, as well as a trial
combining bemcentinib with docetaxel in advanced NSCLC.

BerGenBio is simultaneously developing a companion diagnostic test to identify
patient subpopulations most likely to benefit from treatment with bemcentinib.
This will facilitate more efficient registration trials and support a precision
medicine based commercialization strategy.

The Company is also developing a diversified pre-clinical pipeline of drug
candidates, including BGB149, an anti-AXL monoclonal antibody.

For further information, please visit: www.bergenbio.com

KEYTRUDA® is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary
of Merck & Co., Inc., Kenilworth, NJ, USA, TARCEVA® is a registered trademark of
OSI Pharmaceuticals, LLC., marketed by Roche-Genentech. TAFLINAR® is a
registered trademark of Novartis International AG and MEKINIST® is a registered
trademark of GSK plc.

Contacts

Richard Godfrey
CEO, BerGenBio ASA
+47 917 86 304

Rune Skeie, CFO, BerGenBio ASA
rune.skeie@bergenbio.com
+47 917 86 513

Media Relations in Norway

Jan Petter Stiff, Crux Advisers
stiff@crux.no
+47 995 13 891

International Media Relations

David Dible, Mark Swallow, Marine Perrier, Citigate Dewe Rogerson
bergenbio@citigatedewerogerson.com
+44 207 638 9571

Forward looking statements

This announcement may contain forward-looking statements, which as such are not
historical facts, but are based upon various assumptions, many of which are
based, in turn, upon further assumptions. These assumptions are inherently
subject to significant known and unknown risks, uncertainties and other
important factors. Such risks, uncertainties, contingencies and other important
factors could cause actual events to differ materially from the expectations
expressed or implied in this announcement by such forward-looking statements

This information is subject to the disclosure requirements pursuant

Ekstern link: http://www.newsweb.no/index.jsp?messageId=452366

Nyheten er levert av OBI.

http://www.netfonds.no/quotes/release.php?id=20180529.OBI.20180529S10

2 Likes

Av og til sier jeg ting to ganger. Av og til sier jeg ting to ganger. :rofl:

2 Likes

Nyheten er postet via to forskjellige kanaler…

Jeg synes BergenBio virker spennende nå, mandag kan bli en artig dag. Liker tittelen…

Oilimp
Enkelte ting her i livet kan ikke sies for ofte. ;-))

2 Likes

Ser teknisk meget spennende ut nå. Blir noen lodd her.
https://beta.tekinvestor.no/t/vcp-formasjoner/8178/120?u=vcp

1 Like

Formes nytt bullflagg kortsiktig pt.
Mye tyder på at siste mnd’ers bevegelser er et stort bullflagg. Ligger ann til å bryte opp på denne nå.

2 Likes

Skulle akkurat poste om noen var klare for i dag men det er jo fredag… #mandagsfølelse

Tangerte ath allerede i åpningen, med tanke på potensialet ifm presentasjoner kommende uke kan det fort bli eksplosivt. Volumet er en nytelse å se på.

2 Likes

Det blir spennende på mandag. Jeg tror faktisk denne aksjen er undervurdert hos småaksjonærene, jeg tror mange glemmer å regne med effekten av pasientstratifisering ved hjelp av biomarkører i de kommende pivotale studiene. De reelle effekt-tallene kan nok bli ganske mye høyere en de tallene som hittil er publisert, ihvertfall i AML.

Spørmålet er i hvor stor grad biomarkørene korrelerer mot effekt. Selskapet har sagt at det er en korrelasjon, men ikke kommet med tall på i hvor stor grad. Kanskje får vi vite mer på mandag, kanskje må vi vente til neste vinter.

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Hva ser dere etter ifht effekt? Har dere noen måltall dere leter etter?

Selskapet har rapportert 19% ORR i R/R AML, noe som ikke er fantastisk men som likevel er marginalt bedre enn konkurrentene. Det var vel 11 av 35 pasienter som hadde respons.

Dersom man vha. biomarkører kan identifisere de pasientene som vil ha effekt av behandlingen og så kun behandle disse, så vil jo ORR gå opp dramatisk.

3 Likes

Noen som vet når de kommer med nyheter på mandag?:slight_smile:

Før børsen åpner. Konferansesamtale man kan melde seg på 08:30, presentasjonen legges ut kl 8 på nettsidene deres. Men det er også presentasjon i morgen (lørdag).

2 Likes

Ok, mange takk😊

Nå som vi ikke kan påvirke hverandres kjøp og salg… Hvem sitter over helgen?

<— This guy!

3 Likes

Tok en liten post idag etter breakouten som var igår.

Håper på gode nyheter over helgen på ASCO. Så får vi se på mandag om det var smart. Har troen på bra resultater vertfall :+1:

1 Like

Also this guy here :cowboy_hat_face:

bilde

Selvfølgelig sitter vi!

1 Like