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Nordic Nanovector reported a slightly larger operating loss for Q4 than we had expected, but it has been spending heavily on clinical development, which we appreciate. Management guided imminent first patient treatment in the PARADIGME trial, and we still believe it is on track to get the trial data readout and first filing by the end of 2019. We keep our BUY recommendation but have trimmed our target price to NOK135 (NOK145) on the back of revised forecasts.
Slightly higher operating loss in Q4 than expected. The company is in a period of high spending on the clinical development programme; hence we do not see the higher than expected loss as a concern. The Q4 operating loss was cNOK102m, compared to our estimate of a loss of cNOK71m; the deviation was due entirely to higher development costs, while other costs were in line with our estimates.
Development timeline for PARADIGME should hold – but the risk has increased. The company previously announced in December that the first patient treated was imminent, i.e. in Q4 2017. However, it still has yet to happen, and management said at the Q4 presentation that it would issue a press release when the first patient had been dosed. We estimate the company needs to include all c130 patients in the PARADIGME trial before May/June 2019 to meet the data readout and filing commitment, which looks doable to us, but Nordic Nanovector cannot afford any major delays in the recruitment process.
Next major clinical data-point could be ASH 2018. We believe Nordic Nanovector will not report any additional clinical data until ASH 2018 in December, for maximum impact. We expect it to release the final results from the LYMRIT 37-01 trial at the conference (with focus on CR, ORR and DoR), as well as the first clinical data from the DLBCL trial.
We reiterate our BUY recommendation but have trimmed our target price to NOK135 (145) to reflect our forecast changes, primarily for higher clinical development costs.
Full analyse finner du her, NANO 28.04.2018.pdf (549.1 KB)