Stemmer, det var grunnen ja.
Lenge før jeg investerte dessverre, skulle gjerne kjøpt på 12-13 kr i januar -15 og solgt på 10-gangeren før jul -16!
Det er et par ting jeg har angra på her i livet…
- At jeg gifta meg.
- At jeg ikke solgte alt av Nanoaksjer i desember 2016 da den sto i 124 kr …
Det er en stund siden, henviste selvsagt emisjonen og 2016.
Med pcib emisjonen friskt i minnet der jeg i ettertid ser at jeg satt for tungt blir det kun en mindre investering i NANO eventuelt kortsiktig trading med større beløp til eventuelle emisjons-betingelser er offentliggjort. Det der gidder jeg ikke igjen. Jeg forbereder meg til en emisjon med opp til 50% rabatt i worst case. Så får jeg heller løpe etter ved f.eks. emisjon med premie (sjelden kost) eller partneravtale. Samme gjelder BGBIO og TRVX.
Den forrige rettede emisjonen ble vel satt 5% over forrige dags sluttkurs, så en liten premie måtte de gutta betale den gang
For de som frykter at det ikke kommer til å være plass til Betalutin i et marked hvor Car-t finnes:
[Quote]
David Chang, who developed Yescarta[one of two FDA-approved CAR-T therapies] at Kite Pharma, and who used to work for me at Amgen, spent a lot of time talking to me about this. When Kite was acquired by Gilead [Sciences], the maximum throughput in their new facility was six patients a week. I’m not interested in treating six patients a week. I need to treat 100,000 patients. How am I going to do that?
The future for those kinds of therapies is tumor-specific antigens and allogeneic [‘off the shelf’] treatments, so you’ve got something in a bottle.
[ Editors note: A Gilead spokeseman told Xconomy that its El Segundo, CA, manufacturing facility currently has the capacity, at full operation, to produce up to 4,000 CAR-T treatments per year, which would equate to as many as 77 per week. ][/quote]
Veldig godt poeng Savepig, og viktig fokus for hva en investor bør legge vekt på. Selvsagt er kliniske data numero uno, med regulatoriske privilegier som en god styringsparameter.
Men CMC-delen må ikke undervurderes.
CMC står altså for Chemistry, Manufacturing and Control, og kompleksiteten i CMC betyr åpenbart mye for hvor lønnsomt og risikofylt et produkt er. I 99% av alle sammenhenger gjelder det for CMC at desto enklere desto bedre.
Nå mener jeg ikke å underslå at Car-T fremdeles er i veldig tidlig fase og det blir pøst veldig mye penger inn i utvikling og bedre produksjonsmetoder, og det kan fint komme paradigmeskifter der og.
Men det vil ta tid og koste veldig mye penger.
Betalutin og NANO til teknologi forøvrig til sammenligning har jo bare kostet en brøkdel i utvikling, nesten latterlig lite. Et fortrinn at norsk biotech klarer å jobbe så billig, en stor ulempe at vi ikke har muskler til å jobbe mer ekspansivt.
Researchgate er virkelig en skattekiste av en informasjonskilde:
Hvis en trenger noen form for bekreftelse på at de jobber ræva av seg utover de få konferansene som er hvert år:
https://www.researchgate.net/profile/Oyvind_Bruland
https://www.researchgate.net/profile/Jostein_Dahle
https://www.researchgate.net/profile/Ada_Repetto-Llamazares
https://www.researchgate.net/profile/Helen_Heyerdahl
https://www.researchgate.net/scientific-contributions/39067524_Arne_Kolstad
Syntes denne var relevant både for Oncoivent, men også for Nano sitt samarbeid med Orano
Betalutin vil bli NHL svar på Paracetamol. Det første man begynner med er Paracete, så Ibux. Har du fortsatt vondt i hodet går man til legen og får “Car-T”.
(Paracet er det preparatet som fungerer til det meste av lettere smerte, har minst bivirkninger)
Paracet er det preparatet som fungerer til det meste av lettere smerte, har minst bivirkninger)
Og denne teorien er av fundamental verdi?
Magic Bullet Biotech (magicbulletbio)
Nordic Nanovector representeres i mars på konferansen World ADC London av Reza Safaei som skal bygge opp Medical Liaison funksjonen i selskapet.
http://worldadc-europe.com/programme/speakers/
NANO. The launch of Betalutin
The next generation of ADC will be discussed in UK at a conference this spring, and one point is t..
Takk, @Savepig! Hm, nevnte ikke du forleden at her Bravo var innom et sted en mandag for litt siden? Har vært opptatt på annet hold det siste, så jeg har ikke fått fulgt med. Har du du noe i mot å rekapitulere, evt korrigere meg om jeg husker feil?
Tror ikke det Costa var på var så viktig sånn sett, et eller annet generisk spansk næringslivsseminar.
OK, takk for oppklaringen!
24/01-2019 16:33:52: (NANO, NANOO.ST) Nordic Nanovector ASA (OSE: NANO) nomination committee proposes new Chairman
Oslo, Norway, 24 January 2019
In the nomination committee’s recommendation to the Company’s annual general meeting in 2018, it was informed that the chairman of the board, Ludvik Sandnes, wanted to withdraw from his position and that the nomination committee would start work on finding a new chairman of the board.
…Vis børsmeldingen
The nomination committee has identified an experienced and well-suited candidate and proposes that an extraordinary general meeting (“EGM”) should be held to elect Dr. Jan H. Egberts as a new board member and chairman of the board. The Company will summon an EGM for this purpose in due course.
Jan H. Egberts, M.D. has over 25 years of experience in the pharmaceutical and medical devices sector. He gained his medical qualifications from Erasmus University Medical School in the Netherlands and pursued the final year of his medical education at Harvard Medical School in the USA. Dr. Egberts also obtained an MBA from Stanford University in the USA. After Stanford, he joined McKinsey & Co. as a strategic consultant in New York, after which he held various business development and general management positions of increasing responsibility in the USA at Merck & Co. and Johnson & Johnson. Dr Egberts was also the CEO of Octoplus a publicly listed company acquired by Dr. Reddy’s Laboratories.
Dr. Egberts is currently the Managing Partner of Veritas Investments, a family investment firm focused on investments in healthcare companies in the US and Europe. Dr. Egberts also serves as the Chairman of Photocure ASA (Oslo, PHO) and on the board of Pharming (AEX; PHARM). He is on the board of a number of privately held companies and foundations. During his career, Dr. Egberts has held over 20 Supervisory Board positions both in the US and various European countries.
For further information, please contact:
Eduardo Bravo, CEO
Cell: +34 609 481 091
Email: ebravo@nordicnanovector.com
Malene Brondberg, VP Investor Relations and Corporate Communications
Cell: +44 7561 431 762
Email: ir@nordicnanovector.com
International Media Enquiries
Mark Swallow/David Dible (Citigate Dewe Rogerson)
Tel: +44 207 638 9571
Email: nordicnanovector@citigatedewerogerson.com
About Nordic Nanovector
Nordic Nanovector is committed to develop and deliver innovative therapies to patients to address major unmet medical needs and advance cancer care. The Company aspires to become a leader in the development of targeted therapies for haematological cancers. Nordic Nanovector’s lead clinical-stage candidate is Betalutin®, a novel CD37-targeting antibody-radionuclide-conjugate designed to advance the treatment of non-Hodgkin’s lymphoma (NHL). NHL is an indication with substantial unmet medical need, representing a growing market forecast to be worth nearly USD 29 billion by 2026. Nordic Nanovector intends to retain marketing rights and to actively participate in the commercialisation of Betalutin® in core markets. Further information can be found at www.nordicnanovector.com.
This information is subject to a duty of disclosure pursuant to Section 5-12 of the Norwegian Securities Trading Act.
http://www.netfonds.no/quotes/release.php?id=20190124.Cision.20190124:BIT:3093:0
Noen som vet hva Photocure-folket synes om Egberts?
Hadde i det lengste håper på Andrew Kay, men får håpe dette er en bra nummer to.
24/01-2019 16:40:09: (NANO, NANOO.ST) Nordic Nanovector launches a private placement of new shares
Not for general release, publication or distribution, directly or indirectly, in the United States of America, Canada, Japan or Australia
THIS IS A RESTRICTED COMMUNICATION AND YOU MUST NOT FORWARD IT OR ITS CONTENTS TO ANY PERSON TO WHOM FORWARDING THIS COMMUNICATION IS PROHIBITED BY THE LEGENDS CONTAINED HEREIN
…Vis børsmeldingen
Oslo, Norway, 24 January 2019
Nordic Nanovector ASA (OSE: NANO) (“Nordic Nanovector” or the “Company”), a biopharmaceutical company dedicated to extending and improving the lives of patients with haematological cancers through the development and commercialisation of innovative targeted therapeutics, announces the launch of a private placement of new shares representing up to approximately 10% (the “Offer Shares”) of the outstanding share capital of the company (the “Private Placement”). DNB Markets and Jefferies International Limited are acting as Joint Global Coordinators and Joint Bookrunners (the “Joint Global Coordinators”), and Kempen & Co N.V. is acting as Joint Bookrunner (together with the Joint Global Coordinators, the “Joint Bookrunners”) in connection with the Private Placement.
Nordic Nanovector intends to use the net proceeds of the Private Placement for the following purposes:
· Manufacturing development activities (including Process Validation studies) for Betalutin®
· A scale-up of the Company’s clinical and commercial activities in preparation for a commercial launch of Betalutin®
· General corporate purposesThe subscription price and the number of shares to be issued in the Private Placement will be determined through an accelerated bookbuilding process. The bookbuilding period and the application period for the Private Placement commence today at 16:30 hours CET and will close at 08:00 hours CET on 25 January 2019 (the “Application Period”). The Company and the Joint Bookrunners reserve the right to close or extend the Application Period at any time and for any reason. If the Application Period is shortened or extended, any other dates referred to herein may be amended accordingly.
The Company’s largest shareholder, HealthCap VI L.P., has informed the Company that it will participate in the Private Placement.
The minimum subscription and allocation amount in the Private Placement will be the NOK equivalent of EUR 100,000, provided that the Company may, at its sole discretion, allocate an amount below EUR 100,000 to the extent applicable exemptions from the prospectus requirement pursuant to applicable regulations, including the Norwegian Securities Trading Act and ancillary regulations, are available. Allocation of the Offer Shares will be determined at the end of the bookbuilding process, and the final allocation will be made by the Company’s Board of Directors at its sole discretion, following advice from the Joint Bookrunners.
The Offer Shares to be issued in connection with the Private Placement will be issued based on the board authorisation granted at the Company’s annual general meeting on 30 May 2018. In line with the shareholders’ approval, pre-emption rights of the existing shareholders are excluded.
The board of directors of the Company has considered alternative structures for the raising of new equity. Following careful considerations, the board of directors is of the view that the conduct of a private placement because this will, inter alia, strengthen the Company’s shareholder base in future equity raisings. Furthermore, by structuring the transaction as a private placement, the Company will be in a position to raise capital in an efficient manner in a market that is open for capital raisings, and with a lower discount to current trading price and with significantly lower risks compared to a rights issue. In addition, the Private Placement is subject to broad marketing through a pre-sounding and a publicly announced bookbuilding process. By this, a market based subscription price will be achieved.
The board of directors therefore considers a private placement to be in the best interests of the Company and its shareholders.
The Private Placement will be directed towards Norwegian and international investors, in each case subject to and in compliance with applicable exemptions from relevant prospectus or registration requirements. Notification of allotment and payment instructions is expected to be issued to the applicants on or about 25 January 2019 through a notification to be issued by the Joint Bookrunners.
The Offer Shares will be settled with existing and unencumbered shares in the Company that are already listed on the Oslo Stock Exchange, pursuant to a share lending agreement between DNB Markets (on behalf of the Joint Bookrunners), the Company and HealthCap VI L.P., in order to facilitate delivery of listed shares to investors on a delivery versus payment basis. The Offer Shares delivered to the subscribers will thus be tradable from allocation. The Joint Bookrunners will settle the share loan with new shares in the Company to be issued by the Board of Directors pursuant to the abovementioned authorisation granted at the annual general meeting held on 30 May 2018.
The Company has agreed with the Joint Bookrunners to a lock-up on future share issuances, and its Board of Directors and Executive Management have all agreed with the Joint Bookrunners to a lock-up on existing shareholdings for a period of 180 days from the closing date, subject to customary exceptions. In addition, the Company’s largest shareholder, HealthCap VI L.P. has agreed with the Joint Bookrunners to a lock-up for a period of 90 days from the closing date, subject to customary exceptions.
The Company will announce the final number of Offer Shares placed and the final subscription price in the Private Placement in a stock exchange announcement expected to be published before opening of trading on the Oslo Stock Exchange tomorrow, 25 January 2019. Completion of the Private Placement is subject to final approval by the Company’s Board of Directors.
For further information, please contact:
Eduardo Bravo, CEO
Cell: +34 609 481 091
Email: ebravo@nordicnanovector.com
Malene Brondberg, VP Investor Relations and Corporate Communications
Cell: +44 7561 431 762
Email: ir@nordicnanovector.com
International Media Enquiries
Mark Swallow/David Dible (Citigate Dewe Rogerson)
Tel: +44 207 638 9571
Email: nordicnanovector@citigatedewerogerson.com
About Nordic Nanovector
Nordic Nanovector is committed to develop and deliver innovative therapies to patients to address major unmet medical needs and advance cancer care. The Company aspires to become a leader in the development of targeted therapies for haematological cancers. Nordic Nanovector’s lead clinical-stage candidate is Betalutin®, a novel CD37-targeting antibody-radionuclide-conjugate designed to advance the treatment of non-Hodgkin’s lymphoma (NHL). NHL is an indication with substantial unmet medical need, representing a growing market forecast to be worth nearly USD 29 billion by 2026. Nordic Nanovector intends to retain marketing rights and to actively participate in the commercialisation of Betalutin® in core markets. Further information can be found at www.nordicnanovector.com.
This information is subject to a duty of disclosure pursuant to Section 5-12 of the Norwegian Securities Trading Act.
Important Notices
This document is not an offer to sell or a solicitation of offers to purchase or subscribe for shares. Copies of this document may not be sent to jurisdictions, or distributed in or sent from jurisdictions, in which this is barred or prohibited by law. The information contained herein shall not constitute an offer to sell or the solicitation of an offer to buy, in any jurisdiction in which such offer or solicitation would be unlawful absent registration, or an exemption from registration or qualification under the securities laws of any jurisdiction.
This document is not for publication or distribution in the United States of America, Canada, Australia or Japan and it does not constitute an offer or invitation to subscribe for or purchase any securities in such countries or in any other jurisdiction. In particular, the document and the information contained herein should not be distributed or otherwise transmitted into the United States of America or to U.S. persons (as defined in the U.S. Securities Act of 1933, as amended (the “Securities Act”)) or to publications with a general circulation in the United States of America. This document is not an offer for sale of securities in the United States of America. The securities referred to herein have not been and will not be registered under the Securities Act, or the laws of any state, and may not be offered or sold in the United States of America absent registration under or an exemption from registration under the Securities Act. Nordic Nanovector does not intend to register any part of the Private Placement in the United States of America.
There will be no public offering of the securities in the United States of America. Any public offering in the United States of America would be made by means of a prospectus containing detailed information about the company and management, as well as financial statements.
The information contained herein does not constitute an offer of securities to the public in the United Kingdom. No prospectus offering securities to the public will be published in the United Kingdom. This document is only being distributed to and is only directed at (i) persons who are outside the United Kingdom or (ii) to investment professionals falling within article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005 (the “Order”) or (iii) high net worth entities, and other persons to whom it may lawfully be communicated, falling within article 49(2)(a) to (d) of the Order (all such persons together being referred to as “relevant persons”). The securities are only available to, and any invitation, offer or agreement to subscribe, purchase or otherwise acquire such securities will be engaged in only with, relevant persons.
Any person who is not a relevant person should not act or rely on this document or any of its contents. Any offer of securities to the public that may be deemed to be made pursuant to this communication in any member state of the European Economic Area (each an “EEA Member State”) that has implemented Directive 2003/71/EC (together with the 2010 PD Amending Directive 2010/73/EU, including any applicable implementing measures in any Member State, the “Prospectus Directive”) is only addressed to qualified investors in that Member State within the meaning of the Prospectus Directive.
The information contained in this document does not purport to be comprehensive. None of the Joint Bookrunners, any of their respective subsidiary undertakings or affiliates, or their respective directors, officers, employees, advisers or agents accepts any responsibility or liability whatsoever for (whether in contract, tort or otherwise) or makes any representation or warranty, express or implied, as to the truth, accuracy or completeness of the information in this document (or whether any information has been omitted from the document) or any other information relating to the Company, its subsidiaries, affiliates or associated companies, whether written, oral or in a visual or electronic form, and howsoever transmitted or made available or for any loss howsoever arising from any use of this document or its contents or otherwise arising in connection therewith. The Joint Bookrunners disclaim any responsibility for any acts or omissions of the Company, any of the Directors, HealthCap VI L.P. or any other person in connection with the Private Placement.
The Joint Bookrunners are acting for the Company in connection with the Private Placement and no one else and will not be responsible to anyone other than the Company for providing the protections afforded to their respective clients or for providing advice in relation to the Private Placement or any transaction or arrangement referred to in this press release.
Solely for the purposes of the product governance requirements contained within: (a) EU Directive 2014/65/EU on markets in financial instruments, as amended (“MiFID II”); (b) Articles 9 and 10 of Commission Delegated Directive (EU) 2017/593 supplementing MiFID II; and © local implementing measures (together, the “MiFID II Product Governance Requirements”), and disclaiming all and any liability, whether arising in tort, contract or otherwise, which any “manufacturer” (for the purposes of the MiFID II Product Governance Requirements) may otherwise have with respect thereto, the securities described in this press release have been subject to a product approval process, which has determined that such securities are: (i) compatible with an end target market of retail investors and investors who meet the criteria of professional clients and eligible counterparties, each as defined in MiFID II; and (ii) eligible for distribution through all distribution channels as are permitted by MiFID II (the “Target Market Assessment”). Notwithstanding the Target Market Assessment, distributors should note that: the price of the securities may decline and investors could lose all or part of their investment; the securities offer no guaranteed income and no capital protection; and an investment in the securities is compatible only with investors who do not need a guaranteed income or capital protection, who (either alone or in conjunction with an appropriate financial or other adviser) are capable of evaluating the merits and risks of such an investment and who have sufficient resources to be able to bear any losses that may result therefrom. The Target Market Assessment is without prejudice to the requirements of any contractual, legal or regulatory selling restrictions in relation to the Transaction. Furthermore, it is noted that, notwithstanding the Target Market Assessment, the Joint Bookrunners will only approach investors who meet the criteria of professional clients and eligible counterparties.
For the avoidance of doubt, the Target Market Assessment does not constitute: (a) an assessment of suitability or appropriateness for the purposes of MiFID II; or (b) a recommendation to any investor or group of investors to invest in, or purchase, or take any other action whatsoever with respect to the securities. Each distributor is responsible for undertaking its own target market assessment in respect of the securities and determining appropriate distribution channels.
This publication may contain specific forward-looking statements, e.g. statements including terms like “believe”, “assume”, “expect”, “forecast”, “project”, “may”, “could”, “might”, “will” or similar expressions. Such forward -looking statements are subject to known and unknown risks, uncertainties and other factors which may result in a substantial divergence between the actual results, financial situation, development or performance of Nordic Nanovector and those explicitly or implicitly presumed in these statements. Against the background of these uncertainties, readers should not rely on forward-looking statements. Nordic Nanovector assumes no responsibility to update forward -looking statements or to adapt them to future events or developments.
http://www.netfonds.no/quotes/release.php?id=20190124.Cision.20190124:BIT:3099:0
Oi, var ikke det litt tidlig?
Der kom emisjonen!
Jeg stiller meg i utgangspunktet positiv til at de gjør det nå.
Helt fullt mulig at børsene bare kræsjer enda mye mer utover våren. Og jo mer slunken kotoen blir, jo større tyngde har det som bear-argument.
Dette er også helt konsistent med Bravo sitt virke i Tigenix. Enormt opptatt av å skaffe cash når man kan.
Glad for å se at Health cap denne gangen stiller opp, det gjorde de ikke forrige gang.