I agree with you, expectations are high. I remember PW in one of the presentation when he was talking about the translation of results from mice to human said that there is always the risk of under-achieving or even the technology not working in a clinical set up, however he followed by another statement insinuating that the risk is low based on the fact that pci works in a mechanistic way. So for this reason, I believe the results might not be dramatically inferior to what has already been achieved in mice.
Good luck