Gjentar denne:
Er det abscopal effekt de tar opp på mandag i boston?
ufo2308
2
1d
Hvor mange gjennomganger PCIB skal ha i boston vet ikke jeg men nedenfor så ser det ihvertfall ut for å være en på mandag , med 2 stk fra leiden , hmmmm
Forutsatt at dette er PCIB og ikke gruppen fra oslo univ.hospital .
https://spie.org/PDT/conferencedetails/17th-international-photodynamic-association-world-congress
Session 11:
Photodynamic Immune Activation and Immunotherapy
Monday 1 July 2019
10:30 AM - 12:30 PM
Location: Salon 4
Session Chairs:
Ferry Ossendorp, Leiden Univ. Medical Ctr. (Netherlands) ;
Arjan Griffioen, Amsterdam Univ. Medical Ctr. (Netherlands)
Photochemical internalization (PCI) of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity (Invited Paper)
Paper 11070-71
Time: 10:30 AM - 10:50 AM
Author(s): Kristian Berg, Ane Sofie Fremstedal, Anette Weyergang, Oslo Univ. Hospital (Norway); Jakub Golab, Medical Univ. of Warsaw (Poland); Ole-Jacob Norum, Oslo Univ. Hospital (Norway)
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Photochemical internalization (PCI) is a technology enhancing intracellular drug delivery by light-induced translocation of endocytosed therapeutics into the cytosol. PCI of BLM did not induce a curative effect in athymic mice while more than 90% of the thymic mice were cured. Cured thymic mice, re-challenged with CT26.CL25 tumor cells on the contralateral leg, rejected 57-100% of the tumors inoculated up to 2 months after PCI. T-cells from the spleen of PCI-treated mice were found to inhibit the growth of CT26.CL25 cells in naïve thymic mice showing that treatment of CT26.CL25 tumors in thymic mice by PCI induces systemic anti-tumor immunity