I påvente av nyheter sitter jeg å koser meg med uttalelser fra tidligere studier.
Photochemical internalisation shows promise against various malignancies
-Dr. Waseem Jerjes, co-investigator on the study:
“We dealt with a very difficult-to-treat group of patients who exhausted all the available treatment options of surgery, radiotherapy and chemotherapy. PCI showed excellent anti-tumour effect in patients with life expectancy not exceeding few months , yet some of them still lived 4 years after the end of the trial. The PCI-related adverse events were negligible”. He also commented “It was very interesting to see the uniform PCI effect causing tumour death on a number of patients with very aggressive malignancies including squamous cell carcinoma, sarcoma, eccrine (adnexal) carcinoma and chemo-resistant ductal carcinoma”.
Quotes:
- Mr. Colin Hopper, Head of the Academic Unit of Oral and Maxillofacial Surgery at the UCL Eastman Dental Institute:
“The PCI intervention is safe and tolerable by all patients. Significant anti-tumour effects were seen with all the doses tested on several different types of tumours. The acceptance of this study for publication in this prestigious journal shows the quality of this work, and is an indication of the need for new treatment approaches and the interest in the PCI-application.”
-Dr. Rifat Hamoudi, Senior Lecturer within the Centre of Molecular Intervention part of the Department of Tissue & Energy in the Division of Surgery & Interventional Science, :
"The results of this first-in-man study are intriguing as they show that PCI works on various tumours with lower side effects than conventional therapy allowing multiple re-treatments, with no cumulative toxicity. The study warrants further work on the molecular characterisation of PCI treated malignancies providing better understanding of carcinogenesis and the role of tumour heterogeneity in cancer evolution and progression. Findings from the study provide the basis for further investigations leading to the optimisation of PCI enhancing its therapeutic role on wider range of cancers”.
_-Prof. Dr. med. Jörg Trojan, principal investigator University Hospital Frankfurt: _
“Bile duct cancer is a devastating disease with a very clear need of better treatment methods. fimaCHEM represents a novel local treatment approach for inoperable perihilar bile duct cancer patients and a single treatment with the technology has already shown promising early signs of efficacy compared to standard treatment options. It is exciting to explore whether these results can be further improved by repeated fimaCHEM treatments and I look forward to working with my fellow investigators on this study.”
https://www.ucl.ac.uk/surgery/news/2016/sep/photochemical-internalisation-shows-promise-against-various-malignancies
it’s “la vie en rose”
