Snakker du om Ultimovacs? Jeg følger ikke de to så nøye lenger men det fant jeg i Ultimovacs sin melding fra 21.10.
“The Fast Track designation is based on data from two separate Phase I trials of
UV1 in combination with checkpoint inhibitors, either with pembrolizumab (anti-
PD-1) or with ipilimumab (anti-CTLA-4). According to data disclosed recently,
UV1 in combination with pembrolizumab as a first-line treatment in advanced
melanoma was shown to be safe with promising early efficacy data; an objective
response rate (ORR) of 57% was reached with 30% of patients achieving a complete
response (CR), or complete disappearance of their tumors. At 24 months follow
up, 80% of patients were alive. In a second cohort, similar levels of tumor
destruction were seen with 90% of patients remained alive after one year. Peer-
reviewed data published in May 2021 in Frontiers in Immunology demonstrated that
UV1 with ipilimumab was safe and showed signals of prolonged efficacy in
advanced melanoma, the combination achieving ORR of 33% and 5-year overall
survival (OS) rate of 50%.”
Her Targo fått bedre resultater?

