Hvis du ser til Imbruvica (Ibrutinib) hvor museforsøk viser at Alpha37 er superior til dette medikamentet i CLL, så ser man under hvilken årlig omsetning som kommer fra Imbruvica. Det er drug nr 8 på årlig omsetning. Kan man gjenskape dette klinisk snakker vi virkelig om en blockbuster.
Burde vel minst få 3 - 400 MUSD for denne?
Melding om hva man ser fra Alpha37:
Promising efficacy in both ibrutinib-resistant and ibrutinib-sensitive CLL models was observed and treatment with Alpha37 was superior to both ibrutinib and oblinutuzumab, confirming that further clinical development is warranted. These data were previously presented at the company’s R&D Day in November 2021.
8. Imbruvica
Imbruvica
Companies : AbbVie, Johnson & Johnson
Used for : Mantle cell lymphoma, chronic lymphocytic leukemia, Waldenstrom’s macroglobulinemia, marginal zone lymphoma, chronic graft vs. host disease
2019 sales : $7.24 billion
AbbVie and Johnson & Johnson’s Imbruvica has emerged as the top dog in rare blood cancers despite a rush of challengers piling in—a nice recipe for growing sales. But in its most profitable indication, chronic lymphocytic leukemia, that competition is about to get stiffer with a challenger’s recent approval, and another possibly on the way.
AbbVie and J&J’s Imbruvica could add $990 million in sales to its 2019 total of $7.24 billion, according to Evaluate Pharma. That would bring Imbruvica’s sales this year up to $8.23 billion.